Publications of Felix Bröcker

Bennett, A.; Hull, J.; Jolinon, N.; Tordo, J.; Moss, K.; Binns, E.; Mietzsch, M.; Hagemann, C.; Linden, R. M.; Serio, A. et al.; Chipman, P.; Sousa, D.; Bröcker, F.; Seeberger, P. H.; Henckaerts, E.; McKenna, R.; Agbandje-McKenna, M.: Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2. Journal of Structural Biology 213 (4), 107795 (2021)

Mietzsch, M.; Yu, J. C.; Hsi, J.; Chipman, P.; Bröcker, F.; Fuming, Z.; Linhardt, R. J.; Seeberger, P. H.; Heilbronn, R.; McKenna, R. et al.; Agbandje-McKenna, M.: Structural study of AAVrh.10 receptor and antibody interactions. Journal of Virology 95 (23), e01249-21 (2021)

Roderer, D.; Bröcker, F.; Sitsel, O.; Kaplonek, P.; Leidreiter, F.; Seeberger, P. H.; Raunser, S.: Glycan-dependent cell adhesion mechanism of Tc toxins. Nature Communications 11, 2694 (2020)

Bröcker, F.; Wegner, E.; Silva Seco, B. M.; Kaplonek, P.; Bräutigam, M.; Ensser, A.; Pfister, F.; Daniel, C.; Martin, C. E.; Mattner, J. et al.; Seeberger, P. H.: Synthetic oligosaccharide-based vaccines protect mice from clostridioides difficile infections. ACS Chemical Biology 14 (12), pp. 2720 - 2728 (2019)

Bröcker, F.; Götze, S.; Hudon, J.; Rathwell, D. C. K.; Pereira, C. L.; Stallforth, P.; Chakkumkal, A.; Seeberger, P. H.: Synthesis, liposomal formulation, and immunological evaluation of a minimalistic carbohydrate-α-GalCer vaccine candidate. Journal of Medicinal Chemistry 61 (11), pp. 4918 - 4927 (2018)

Bröcker, F.; Seeberger, P. H.: Identification and design of synthetic B cell epitopes for carbohydrate-based vaccines. Methods in Enzymology 597, pp. 311 - 334 (2017)

Hahm, H. S.; Bröcker, F.; Kawasaki, F.; Mietzsch, M.; Heilbronn, R.; Fukuda, M.; Seeberger, P. H.: Automated glycan assembly of oligo-N-acetyllactosamine and keratan sulfate probes to study virus-glycan interactions. Chem 2 (1), pp. 114 - 124 (2017)

Bröcker, F.; Horton, R.; Heinrich, J.; Franz, A.; Schweiger, M.-R.; Lehrach, H.; Moelling, K.: The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation. Mobile DNA 7, 25 (2016)

Bröcker, F.; Martin, C. E.; Wegner, E.; Mattner, J.; Baek, J. Y.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: Synthetic lipoteichoic acid glycans are potential vaccine candidates to protect from Clostridium difficile infections. Cell Chemical Biology 23 (8), pp. 1014 - 1022 (2016)

Broecker, F.; Hanske, J.; Martin, C. E.; Baek, J. Y.; Wahlbrink, A.; Wojcik, F.; Hartmann, L.; Rademacher, C.; Chakkumkal, A.; Seeberger, P. H.: Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans. Nature Communications 7, 11224 (2016)

Broecker, F.; Klumpp, J.; Moelling, K.: Long-term microbiota and virome in a Zürich patient after fecal transplantation against Clostridium difficile infection. Annals of the New York Academy of Sciences 1372 (1), pp. 29 - 41 (2016)

Möginger, U.; Resemann, A.; Martin, C. E.; Parameswarappa, S.; Govindan, S.; Wamhoff, E.-C.; Broecker, F.; Suckau, D.; Pereira, C. L.; Chakkumkal, A. et al.; Seeberger, P. H.; Kolarich, D.: Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports 6, 20488 (2016)

Mölling, K.; Bröcker, F.: Fecal microbiota transplantation to fight Clostridium difficile infections and other intestinal diseases. Bacteriophage 6 (4), e1251380 (2016)

Moelling, K.; Bröcker, F.: The reverse transcriptase-RNase H: from viruses to antiviral defense. Annals of the New York Academy of Sciences 1341 (1), pp. 126 - 135 (2015)

Bröcker, F.; Aretz, J.; Yang, Y.; Hanske, J.; Guo, X.; Reinhardt, A.; Wahlbrink, A.; Rademacher, C.; Anish, C.; Seeberger, P. H.: Epitope recognition of antibodies against a Yersinia pestis lipopolysaccharide trisaccharide component. ACS Chemical Biology 9 (4), pp. 867 - 873 (2014)

Mietzsch, M.; Broecker, F.; Reinhardt, A.; Seeberger, P. H.; Heilbronn, R.: Differential adeno-associated virus serotype-specific interaction patterns with synthetic heparins and other glycans. Journal of Virology 88 (5), pp. 2991 - 3003 (2014)

Mitrovic, J.; Siewert, C.; Duduk, B.; Hecht, J.; Mölling, K.; Broecker, F.; Beyerlein, P.; Büttner, C.; Bertaccini, A.; Kube, M.: Generation and analysis of draft sequences of 'Stolbur' phytoplasma from multiple displacement amplification templates. Journal of Molecular Microbiology and Biotechnology 24 (1), pp. 1 - 11 (2014)

Wallbrecher, R.; Verdurmen, W. P. R.; Schmidt, S.; Bovee-Geurts, P. H.; Bröcker, F.; Reinhardt, A.; van Kuppevelt, T. H.; Seeberger, P. H.; Brock, R.: The stoichiometry of peptide-heparan sulfate binding as a determinant of uptake efficiency of cell-penetrating peptides. Cellular and Molecular Life Sciences 71 (14), pp. 2717 - 2729 (2014)

Broecker, F.; Kube, M.; Klumpp, J.; Schuppler, M.; Biedermann, L.; Hecht, J.; Hombach, M.; Keller, P. M.; Rogler, G.; Moelling, K.: Analysis of the Intestinal Microbiome of a Recovered Clostridium difficile Patient after Fecal Transplantation. Digestion 88 (4), pp. 243 - 251 (2013)

Martin, C. E.; Broecker, F.; Eller, S.; Oberli, M. A.; Anish, C.; Pereira, C. L.; Seeberger, P. H.: Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine. Chemical Communications 49 (64), pp. 7159 - 7161 (2013)