Welcome to the Mailänder Laboratory
The focus of our group is the use of nanocarriers for protection and controlled release of drugs and thus harnessing 10-300 nm sized "containers" for drug delivery in humans. Therefore, we focus on the interaction of nanoparticles with human cells as a drug delivery device by looking at:
- adhesion and uptake of nanoparticles
- fate after endocytosis, trafficking and exocytosis of nanoparticles
- targeting specific populations of cells in vivo as well as ex vivo and controlled release in the target cell
- cells of the immune system, human stem cells (hematopoietic and mesenchymal) or tumor cells