Publications of Ivan Đikić

Bailey, H. J.; Eisert, J.; Kazi, R.; Gerhartz, J.; Pieńkowska, D. E.; Dressel, I.; Vollrath, J.; Kondratov, I.; Matviyuk, T.; Tolmachova, N. et al.; Shah, V. J.; Giuliani, G.; Mosler, T.; Geiger, T. M.; Esteves, A. M.; Santos, S. P.; Sousa, R. L.; Bandeiras, T. M.; Leibrock, E.-M.; Bauer, U.; Leuthner, B.; Langer, J. D.; Wegener, A. A.; Nowak, R. P.; Sorrell, F. J.; Đikić, I.: An engineered cereblon optimized for high throughput screening and molecular glue discovery. Cell Chemical Biology 32 (2), pp. 363 - 376.e10 (2025)

Herhaus, L.; Gestal-Mato, U.; Eapen, V. V.; Mačinković, I.; Bailey, H. J.; Prieto-Garcia, C.; Misra, M.; Jacomin, A.-C.; Ammanath, A. V.; Bagarić, I. et al.; Michaelis, J.; Vollrath, J.; Bhaskara, R. M.; Bündgen, G.; Covarrubias-Pinto, A.; Husnjak, K.; Zöller, J.; Gikandi, A.; Ribičić, S.; Bopp, T.; van der Heden van Noort, G. J.; Langer, J. D.; Weigert, A.; Harper, J. W.; Mancias, J. D.; Đikić, I.: IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion. Cell 187 (7), pp. 7285 - 7302 (2024)

Prieto-Garcia, C.; Matkovic, V.; Mosler, T.; Li, C.; Liang, J.; Oo, J. A.; Haidle, F.; Mačinković, I.; Cabrera-Orefice, A.; Berkane, R. et al.; Giuliani, G.; Xu, F.; Jacomin, A.-C.; Tomaskovic, I.; Basoglu, M.; Hoffmann, M. E.; Rathore, R.; Cetin, R.; Boutguetait, D.; Bozkurt, S.; Hernández Cañás, M. C.; Keller, M.; Busam, J.; Shah, V. J.; Wittig, I.; Kaulich, M.; Beli, P.; Galej, W. P.; Ebersberger, I.; Wang, L.; Münch, C.; Stolz, A.; Brandes, R. P.; Tse, W. K. F.; Eimer, S.; Stainier, D. Y. R.; Legewie, S.; Zarnack, K.; Müller-McNicoll, M.; Dikic, I.: Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy. Science 386 (6723), pp. 768 - 776 (2024)

Mukherjee, R.; Bhattacharya, A.; Mello-Vieira, J.; Kuncha, S. K.; Hoffmann, M.; Gonzalez, A.; Rathore, R.; Chadha, A.; Shin, D.; Colby, T. et al.; Matic, I.; Mukherjee, S.; Misra, M.; Dikic, I.: Serine ubiquitination of SQSTM1 regulates NFE2L2-dependent redox homeostasis. Autophagy (2024)

Xavier, A.; Đikić, I.: Feeding cancer to death - a triad of aromatic acids reduces tumor growth. Cell Death & Differentiation 31, pp. 1239 - 1241 (2024)

Kew, C.; Prieto-Garcia, C.; Bhattacharya, A.; Tietgen, M.; MacNair, C. R.; Carfrae, L. A.; Mello-Vieira, J.; Klatt, S.; Cheng, Y.-L.; Rathore, R. et al.; Gradhand, E.; Fleming, I.; Tan, M.-W.; Göttig, S.; Kempf, V. A. J.; Đikić, I.: The aryl hydrocarbon receptor and FOS mediate cytotoxicity induced by Acinetobacter baumannii. Nature Communications 15, 7939 (2024)

Mello-Vieira, J.; Bopp, T.; Đikić, I.: Ubiquitination and cell-autonomous immunity. Current Opinion in Immunology 84, 102368 (2023)

Bhattacharya, A.; Mukherjee, R.; Kuncha, S. K.; Brunstein, M. E.; Rathore, R.; Junek, S.; Münch, C.; Đikić, I.: A lysosome membrane regeneration pathway depends on TBC1D15 and autophagic lysosomal reformation proteins. Nature Cell Biology 25 (5), pp. 685 - 698 (2023)

Krause, D. S.; Dikic, I.: Mycobacterium tuberculosis hijacks ubiquitin to inhibit pyroptosis. Molecular Cell 82 (24), pp. 4588 - 4590 (2022)

Oo, J. A.; Pálfi, K.; Warwick, T.; Wittig, I.; Prieto-Garcia, C.; Matkovic, V.; Tomašković, I.; Boos, F.; Izquierdo Ponce, J.; Teichmann, T. et al.; Petriukov, K.; Haydar, S.; Maegdefessel, L.; Wu, Z.; Pham, M. D.; Krishnan, J.; Baker, A. H.; Günther, S.; Ulrich, H. D.; Đikić, I.; Leisegang, M. S.; Brandes, R. P.: Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell Reports: Methods 41 (7), 111670 (2022)

Shah, V. J.; Đikić, I.: Localization matters in targeted protein degradation. Cell Chemical Biology 29 (10), pp. 1465 - 1466 (2022)

Mukherjee, R.; Dikic, I.: Regulation of Host-Pathogen Interactions via the Ubiquitin System. Annual Review of Microbiology 76, pp. 211 - 233 (2022)

Tiku, V.; Kew, C.; Kofoed, E. M.; Peng, Y.; Đikić, I.; Tan, M.-W.: Acinetobacter baumannii Secretes a Bioactive Lipid That Triggers Inflammatory Signaling and Cell Death. Frontiers in Microbiology 13, 870101 (2022)

Gubas, A.; Dikic, I.: ER remodeling via ER-phagy. Molecular Cell 82 (8), pp. 1492 - 1500 (2022)

Gubas, A.; Đikić, I.: A guide to the regulation of selective autophagy receptors. The FEBS Journal 289 (1), pp. 75 - 89 (2022)

Mukherjee, R.; Bhattacharya, A.; Bojkova, D.; Mehdipour, A. R.; Shin, D.; Khan, K. S.; Hei-Yin Cheung, H.; Wong, K.-B.; Ng, W.; Cinatl, J. et al.; Geurink, P. P.; van der Heden van Noort, G. J.; Rajalingam, K.; Ciesek, S.; Hummer, G.; Dikic, I.: Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection. The Journal of Biological Chemistry 297 (2), 100925 (2021)

Armstrong, L. A.; Lange, S. M.; Dee Cesare, V.; Matthews, S. P.; Nirujogi, R. S.; Cole, I.; Hope, A.; Cunningham, F.; Toth, R.; Mukherjee, R. et al.; Bojkova, D.; Gruber, F.; Gray, D.; Wyatt, P. G.; Cinatl, J.; Đikić, I.; Davies, P.; Kulathu, Y.: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies. PLoS One 16 (7), e0253364 (2021)

Kannt, A.; Đikić, I.: Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation. Cell Chemical Biology 28 (7), pp. 1014 - 1031 (2021)

Gubas, A.; Karantanou, C.; Popovic, D.; Tascher, G.; Hoffmann, M. E.; Platzek, A.; Dawe, N.; Dikic, I.; Krause, D. S.; McEwan, D. G.: The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways. FEBS Letters 595 (7), pp. 864 - 880 (2021)

Siggel, M.; Bhaskara, R.; Moesser, M. K.; Đikić, I.; Hummer, G.: FAM134B-RHD Protein Clustering Drives Spontaneous Budding of Asymmetric Membranes. The Journal of Physical Chemistry Letters 12 (7), pp. 1926 - 1931 (2021)