Publications of Christine Ziegler

Koshy, C.; Ziegler, C.: Structural insights into functional lipid–protein interactions in secondary transporters. Biochimica et Biophysica Acta (BBA) - General Subjects 1850 (3), pp. 476 - 487 (2015)

Schweikhard, E. S.; Burckhardt, B. C.; Joos, F.; Fenollar-Ferrer, C.; Forrest, L. R.; Kempson, S. A.; Ziegler, C.: Role of N-glycosylation in renal betaine transport. Biochemical Journal 470 (2), pp. 169 - 179 (2015)

Spindler, P. E.; Waclawska, I.; Endeward, B.; Plackmeyer, J.; Ziegler, C.; Prisner, T. F.: Carr−Purcell Pulsed Electron Double Resonance with Shaped Inversion Pulses. The Journal of Physical Chemistry 6 (21), pp. 4331 - 4335 (2015)

Perez, C.; Faust, B.; Mehdipour, A. R.; Francesconi, K. A.; Forrest, L. R.; Ziegler, C.: Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na⁺ coupling. Nature Communications 5, 4231 (2014)

Sand, M.; Stahl, J.; Waclawska, I.; Ziegler, C.; Averhoff, B.: Identification of an osmo-dependent and an osmo-independent choline transporter in Acinetobacter baylyi: implications in osmostress protection and metabolic adaptation. Environmental Microbiology 16 (6), pp. 1490 - 1502 (2014)

Keller, R.; Ziegler, C.; Schneider, D.: When two turn into one: evolution of membrane transporters from half modules. Biological Chemistry 395 (12), pp. 1379 - 1388 (2014)

Schweikhard, E. S.; Kempson, S. A.; Ziegler, C.; Burckhardt, B. C.: Mutation of a single threonine in the cytoplasmic NH2 terminus disrupts trafficking of renal betaine-GABA transporter 1 during hypertonic stress. American Journal of Physiology - Renal Physiology 307 (1), pp. F107 - F115 (2014)

Koshy, C.; Schweikhard, E. S.; Gärtner, R. M.; Perez, C.; Yildiz, Ö.; Ziegler, C.: Structural evidence for functional lipid interactions in the betaine transporter BetP. The EMBO Journal 32 (23), pp. 3096 - 3105 (2013)

Perez, C.; Ziegler, C.: Mechanistic aspects of sodium-binding sites in LeuT-like fold symporters. Biological Chemistry 394 (5), pp. 641 - 648 (2013)

Korkmaz, F.; Ressl, S.; Ziegler, C.; Mäntele, W.: K⁺-induced conformational changes in the trimeric betaine transporter BetP monitored by ATR-FTIR spectroscopy. Biochimica et Biophysica Acta-Biomembranes 1828 (4), pp. 1181 - 1191 (2013)

Khafizov, K.; Perez, C.; Koshy, C.; Quick, M.; Fendler, K.; Ziegler, C.; Forrest, L. R.: Investigation of the sodium binding sites in the betaine transporter BetP. Proceedings of the National Academy of Sciences of the United States of America 109 (44), pp. E3035 - E3045 (2012)

Perez, C.; Koshy, C.; Yildiz, Ö.; Ziegler, C.: Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP. Nature 490, pp. 126 - 130 (2012)

Schweikhard, E. S.; Ziegler, C. M.: Chapter One – Amino Acid Secondary Transporters: Toward a Common Transport Mechanism. Current Topics in Membranes 70, pp. 1 - 28 (2012)

Marinelli, F.; Kuhlmann, S.; Grell, E.; Kunte, H.-J.; Ziegler, C.; Faraldo-Gómez, J. D.: Evidence for an allosteric mechanism of substrate release from membrane-transporter accessory binding proteins. Proceedings of the National Academy of Sciences of the United States of America 108 (49), pp. E1285 - E1292 (2011)

Gärtner, R. M.; Perez, C.; Koshy, C.; Ziegler, C.: Role of Bundle Helices in a Regulatory Crosstalk in the Trimeric Betaine Transporter BetP. Journal of Molecular Biology 414 (3), pp. 327 - 336 (2011)

Ge, L.; Perez, C.; Waclawska, I.; Ziegler, C.; Muller, D. J.: Locating an extracellular K⁺-dependent interaction site that modulates betaine-binding of the Na⁺-coupled betaine symporter BetP. Proceedings of the National Academy of Sciences of the United States of America 108 (43), pp. E890 - E898 (2011)

Perez, C.; Khafizov, K.; Forrest, L. R.; Krämer, R.; Ziegler, C.: The role of trimerization in the osmoregulated betaine transporter BetP. EMBO Reports 12 (8), pp. 804 - 810 (2011)

Perez, C.; Koshy, C.; Ressl, S.; Nicklisch, S.; Krämer, R.; Ziegler, C.: Substrate specificity and ion coupling in the Na⁺/betaine symporter BetP. EMBO Journal 30, pp. 1221 - 1229 (2011)

Tsai, C.-J.; Khafizov, K.; Hakulinen, J.; Forrest, L. R.; Krämer, R.; Kühlbrandt, W.; Ziegler, C.: Structural Asymmetry in a Trimeric Na⁺/Betaine Symporter, BetP, from Corynebacterium glutamicum. Journal of Molecular Biology 407 (3), pp. 368 - 381 (2011)

Forrest, L. R.; Krämer, R.; Ziegler, C.: The structural basis of secondary active transport mechanisms. Biochimica et Biophysica Acta, Bioenergetics 1807 (2), pp. 167 - 188 (2011)