Publications of Christopher E. Martin

Bröcker, F.; Wegner, E.; Silva Seco, B. M.; Kaplonek, P.; Bräutigam, M.; Ensser, A.; Pfister, F.; Daniel, C.; Martin, C. E.; Mattner, J. et al.; Seeberger, P. H.: Synthetic oligosaccharide-based vaccines protect mice from clostridioides difficile infections. ACS Chemical Biology 14 (12), pp. 2720 - 2728 (2019)

Geißner, A.; Reinhardt, A.; Rademacher, C.; Johannssen, T.; Monteiro, J.; Lepenies, B.; Thépaut, M.; Fieschi, F.; Mrázková, J.; Wimmerova, M. et al.; Schuhmacher, F.; Götze, S.; Grünstein, D.; Guo, X.; Hahm, H. S.; Kandasamy, J.; Leonori, D.; Martin, C. E.; Parameswarappa, S. G.; Pasari,, S.; Schlegel, M. K.; Tanaka, H.; Xiao, G.; Yang, Y.; Pereira, C. L.; Anish, C.; Seeberger, P. H.: Microbe-focused glycan array screening platform. Proceedings of the National Academy of Sciences of the United States of America 116 (6), pp. 1958 - 1967 (2019)

Lisboa, M. P.; Khan, N.; Martin, C.; Xu, F.-F.; Reppe, K.; Geissner, A.; Govindan, S.; Witzenrath, M.; Pereira, C. L.; Seeberger, P. H.: Semisynthetic glycoconjugate vaccine candidate against Streptococcus pneumoniae serotype 5. Proceedings of the National Academy of Sciences of the United States of America 114 (42), pp. 11063 - 11068 (2017)

Bröcker, F.; Martin, C. E.; Wegner, E.; Mattner, J.; Baek, J. Y.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: Synthetic lipoteichoic acid glycans are potential vaccine candidates to protect from Clostridium difficile infections. Cell Chemical Biology 23 (8), pp. 1014 - 1022 (2016)

Broecker, F.; Hanske, J.; Martin, C. E.; Baek, J. Y.; Wahlbrink, A.; Wojcik, F.; Hartmann, L.; Rademacher, C.; Chakkumkal, A.; Seeberger, P. H.: Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans. Nature Communications 7, 11224 (2016)

Möginger, U.; Resemann, A.; Martin, C. E.; Parameswarappa, S.; Govindan, S.; Wamhoff, E.-C.; Broecker, F.; Suckau, D.; Pereira, C. L.; Chakkumkal, A. et al.; Seeberger, P. H.; Kolarich, D.: Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports 6, 20488 (2016)

Zacco, E.; Chakkumkal, A.; Martin, C. E.; von Berlepsch, H.; Brandenburg, E.; Seeberger, P. H.; Koksch, B.: A self-assembling peptide scaffold for the multivalent presentation of antigens. Biomacromolecules 16 (7), pp. 2188 - 2197 (2015)

Anish, C.; Martin, C. E.; Wahlbrink, A.; Bogdan, C.; Ntais, P.; Antoniou, M.; Seeberger, P. H.: Immunogenicity and diagnostic potential of synthetic antigenic cell surface glycans of Leishmania. ACS Chemical Biology 8 (11), pp. 2412 - 2422 (2013)

Martin, C. E.; Broecker, F.; Eller, S.; Oberli, M. A.; Anish, C.; Pereira, C. L.; Seeberger, P. H.: Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine. Chemical Communications 49 (64), pp. 7159 - 7161 (2013)

Martin, C. E.; Broecker, F.; Oberli, M. A.; Komor, J.; Mattner, J.; Anish, C.; Seeberger, P. H.: Immunological evaluation of a synthetic Clostridium difficile oligosaccharide conjugate vaccine candidate and identification of a minimal epitope. Journal of the American Chemical Society 135 (26), pp. 9713 - 9722 (2013)

Yang, Y.; Oishi, S.; Martin, C. E.; Seeberger, P. H.: Diversity-oriented synthesis of inner core oligosaccharides of the lipopolysaccharide of pathogenic Gram-negative bacteria. Journal of the American Chemical Society 135 (16), pp. 6262 - 6271 (2013)

Yang, Y.; Martin, C. E.; Seeberger, P. H.: Total synthesis of the core tetrasaccharide of Neisseria meningitidis lipopolysaccharide, a potential vaccine candidate for meningococcal diseases. Chemical Science 3 (3), pp. 896 - 899 (2012)

Martin, C. E.; Weishaupt, M. W.; Seeberger, P. H.: Progress toward developing a carbohydrate-conjugate vaccine against Clostridium difficile ribotype 027: synthesis of the cell-surface polysaccharide PS-I repeating unit. Chemical Communications 47 (37), pp. 10260 - 10262 (2011)

Bröcker, F.; Martin, C.; Hanske, J.; Rademacher, C.; Pereira, C. L.; Anish, C.; Seeberger, P. H.: Deciphering glycan-antibody interactions: towards a carbohydrate-based vaccine against Clostridium difficile. In Glycobiology, 24 (11), p. 1129 - 1129. Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, HI, November 16, 2014 - November 19, 2014. Oxford University Press, Oxford (2014)

Martin, C. E.: Chemical synthesis and biological evaluation of cell surface carbohydrate antigens for rational vaccine design. Dissertation, Freie Universität Berlin, Berlin (2014)

Chakkumkal, A.; Lisboa, M.; Martin, C. E.; Pereira, C. L.; Seeberger, P. H.; Khan, N.: Vaccines against Streptococcus pneumoniae serotype 5. WO2016198170 (2016)

Seeberger, P. H.; Martin, C. E.; Bröcker, F.; Chakkumkal, A.: Antibodies for prevention and treatment of diseases caused by Clostridium difficile. (2016)

Seeberger, P. H.; Martin, C. E.; Bröcker, F.; Chakkumkal, A.: Oligosaccharides and oligosaccharides-protein conjugates derived from clostridium difficile polysaccharide PS-I, methods of synthesis and uses thereof, in particular as vaccines and diagnostic tools. EP2739636 (2013)