Publications of Chakkumkal Anish

Wrage, M.; Holland, T.; Nüse, B.; Kaltwasser, J.; Fröhlich, J.; Arnold, H.; Gießler, C.; Flamann, C.; Bruns, H.; Berges, J. et al.; Daniel, C.; Hoffmann, M. H.; Anish, C.; Seeberger, P. H.; Bogdan, C.; Dettmer, K.; Rauh, M.; Mattner, J.: Cell type-specific modulation of metabolic, immune-regulatory, and anti-microbial pathways by CD101. Mucosal immunology, pp. 892 - 910 (2024)

Geißner, A.; Reinhardt, A.; Rademacher, C.; Johannssen, T.; Monteiro, J.; Lepenies, B.; Thépaut, M.; Fieschi, F.; Mrázková, J.; Wimmerova, M. et al.; Schuhmacher, F.; Götze, S.; Grünstein, D.; Guo, X.; Hahm, H. S.; Kandasamy, J.; Leonori, D.; Martin, C. E.; Parameswarappa, S. G.; Pasari,, S.; Schlegel, M. K.; Tanaka, H.; Xiao, G.; Yang, Y.; Pereira, C. L.; Anish, C.; Seeberger, P. H.: Microbe-focused glycan array screening platform. Proceedings of the National Academy of Sciences of the United States of America 116 (6), pp. 1958 - 1967 (2019)

Bröcker, F.; Götze, S.; Hudon, J.; Rathwell, D. C. K.; Pereira, C. L.; Stallforth, P.; Chakkumkal, A.; Seeberger, P. H.: Synthesis, liposomal formulation, and immunological evaluation of a minimalistic carbohydrate-α-GalCer vaccine candidate. Journal of Medicinal Chemistry 61 (11), pp. 4918 - 4927 (2018)

Schumann, B.; Reppe, K.; Kaplonek, P.; Wahlbrink, A.; Chakkumkal, A.; Witzenrath, M.; Pereira, C. L.; Seeberger, P. H.: Development of an efficacious, semisynthetic glycoconjugate vaccine candidate against Streptococcus pneumoniae serotype 1. ACS Central Science 4 (3), pp. 357 - 361 (2018)

Schumann, B.; Hahm, H. S.; Parameswarappa, S. G.; Reppe, K.; Wahlbrink, A.; Govindan, S.; Kaplonek, P.; Pirofski, L.-a.; Witzenrath, M.; Chakkumkal, A. et al.; Pereira, C. L.; Seeberger, P. H.: A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine. Science Translational Medicine 9 (380), eaaf5347 (2017)

Bröcker, F.; Martin, C. E.; Wegner, E.; Mattner, J.; Baek, J. Y.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: Synthetic lipoteichoic acid glycans are potential vaccine candidates to protect from Clostridium difficile infections. Cell Chemical Biology 23 (8), pp. 1014 - 1022 (2016)

Broecker, F.; Hanske, J.; Martin, C. E.; Baek, J. Y.; Wahlbrink, A.; Wojcik, F.; Hartmann, L.; Rademacher, C.; Chakkumkal, A.; Seeberger, P. H.: Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans. Nature Communications 7, 11224 (2016)

Geißner, A.; Pereira, C. L.; Leddermann, M.; Chakkumkal, A.; Seeberger, P. H.: Deciphering antigenic determinants of Streptococcus pneumoniae serotype 4 capsular polysaccharide using synthetic oligosaccharides. ACS Chemical Biology 11 (2), pp. 335 - 344 (2016)

Möginger, U.; Resemann, A.; Martin, C. E.; Parameswarappa, S.; Govindan, S.; Wamhoff, E.-C.; Broecker, F.; Suckau, D.; Pereira, C. L.; Chakkumkal, A. et al.; Seeberger, P. H.; Kolarich, D.: Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports 6, 20488 (2016)

Parameswarappa, S. G.; Reppe, K.; Geißner, A.; Ménová, P.; Govindan, S.; Calow, A. D. J.; Wahlbrink, A.; Weishaupt, M. W.; Monnanda, B. P.; Bell, R. et al.; Pirofski, L.-A.; Suttorp, N.; Sander, L.; Witzenrath, M.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: A semi-synthetic oligosaccharide conjugate vaccine candidate confers protection against Streptococcus pneumoniae serotype 3 infection. Cell Chemical Biology 23 (11), pp. 1407 - 1416 (2016)

Reinhardt, A.; Wehle, M.; Geißner, A.; Crouch, E. C.; Kang, Y.; Yang, Y.; Chakkumkal, A.; Santer, M.; Seeberger, P. H.: Structure binding relationship of human surfactant protein D and various lipopolysaccharide inner core structures. Journal of Structural Biology 195 (3), pp. 387 - 395 (2016)

Wörmann, X.; Lesch, M.; Welke, R.-W.; Okonechnikov, K.; Abdurishid, M.; Sieben, C.; Geißner, A.; Brinkmann, V.; Kastner, M.; Karner, A. et al.; Zhu, R.; Hinterdorfer, P.; Chakkumkal, A.; Seeberger, P. H.; Herrmann, A.; Meyer, T. F.; Karlas, A.: Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells. Virology 492, pp. 118 - 129 (2016)

Pereira, C. L.; Geißner, A.; Chakkumkal, A.; Seeberger, P. H.: Chemical synthesis elucidates the immunological importance of a pyruvate modification in the capsular polysaccharide of Streptococcus pneumoniae serotype 4. Angewandte Chemie International Edition 54, pp. 10016 - 10019 (2015)

Reinhardt, A.; Yang, Y.; Claus, H.; Pereira, C. L.; Cox, A. D.; Vogel, U.; Anish, C.; Seeberger, P. H.: Antigenic potential of a highly conserved Neisseria meningitidis lipopolysaccharide inner core structure defined by chemical synthesis. Chemistry & Biology 22 (1), pp. 38 - 49 (2015)

Zacco, E.; Chakkumkal, A.; Martin, C. E.; von Berlepsch, H.; Brandenburg, E.; Seeberger, P. H.; Koksch, B.: A self-assembling peptide scaffold for the multivalent presentation of antigens. Biomacromolecules 16 (7), pp. 2188 - 2197 (2015)

Anish, C.; Schumann, B.; Pereira, C. L.; Seeberger, P. H.: Chemical biology approaches to designing defined carbohydrate vaccines. Chemistry & Biology 21 (1), pp. 38 - 50 (2014)

Bröcker, F.; Aretz, J.; Yang, Y.; Hanske, J.; Guo, X.; Reinhardt, A.; Wahlbrink, A.; Rademacher, C.; Anish, C.; Seeberger, P. H.: Epitope recognition of antibodies against a Yersinia pestis lipopolysaccharide trisaccharide component. ACS Chemical Biology 9 (4), pp. 867 - 873 (2014)

Geißner, A.; Anish, C.; Seeberger, P. H.: Glycan arrays as tools for infectious disease research. Current Opinion in Chemical Biology 18, pp. 38 - 45 (2014)

Götze, S.; Azzouz, N.; Tsai, Y.-H.; Groß, U.; Reinhardt, A.; Anish, C.; Seeberger, P. H.; Silva, D. V.: Diagnosis of toxoplasmosis using a synthetic glycosylphosphatidylinositol glycan. Angewandte Chemie International Edition 53 (50), pp. 13701 - 13705 (2014)

Schumann, B.; Pragani, R.; Anish, C.; Pereira, C. L.; Seeberger, P. H.: Synthesis of conjugation-ready zwitterionic oligosaccharides by chemoselective thioglycoside activation. Chemical Science 5 (5), pp. 1992 - 2002 (2014)