Publications of Ulrich Ermler

Huang, G.; Wagner, T.; Ermler, U.; Shima, S.: Methanogenesis involves direct hydride transfer from H₂ to an organic substrate. Nature Reviews Chemistry 4 (2), pp. 213 - 221 (2020)

Brünle, S.; Eisinger, M. L.; Poppe, J.; Mills, D. J.; Langer, J. D.; Vonck, J.; Ermler, U.: Molybdate pumping into the molybdenum storage protein via an ATP-powered piercing mechanism. Proceedings of the National Academy of Sciences of the United States of America 52 (116), pp. 26497 - 26504 (2019)

Huang, G.; Wagner, T.; Wodrich, M. D.; Ataka, K.; Bill, E.; Ermler, U.; Hu, X.; Shima, S.: The atomic-resolution crystal structure of activated [Fe]-hydrogenase. Nature Catalysis 2 (6), pp. 537 - 543 (2019)

Willistein, M.; Bechtel, D. F.; Müller, C. S.; Demmer, U.; Heimann, L.; Kayastha, K.; Schünemann, V.; Pierik, A. J.; Ullmann, G. M.; Ermler, U. et al.; Boll, M.: Low potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactorsLow potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactors. Nature Communications 10, 2074 (2019)

Watanabe, T.; Wagner, T.; Huang, G.; Kahnt, J.; Ataka, K.; Ermler, U.; Shima, S.: The Bacterial [Fe]‐Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates. Angewandte Chemie International Edition in English 58 (11), pp. 3506 - 3510 (2019)

Poppe, J.; Brünle, S.; Hail, R.; Wiesemann, K.; Schneider, K.; Ermler, U.: The Molybdenum Storage Protein: A soluble ATP hydrolysis‐dependent molybdate pump. The FEBS Journal 285 (24), pp. 4602 - 4616 (2018)

Brünle, S.; Poppe, J.; Hail, R.; Demmer, U.; Ermler, U.: The molybdenum storage protein - A bionanolab for creating experimentally alterable polyoxomolybdate clusters. Journal of Inorganic Biochemistry 189 (12), pp. 172 - 179 (2018)

Wagner , T.; Huang, G.; Ermler, U.; Shima, S.: How [Fe]-Hydrogenase from Methanothermobacter is Protected Against Light and Oxidative Stress. Angewandte Chemie International Edition in English 57 (46), pp. 15056 - 15059 (2018)

Huang, G.; Wagner, T.; Ermler, U.; Bill, E.; Ataka, K.; Shima, S.: Dioxygen Sensitivity of [Fe]‐Hydrogenase in the Presence of Reducing Substrates. Angewandte Chemie International Edition in English 57 (18), pp. 4917 - 4920 (2018)

Demmer, J. K.; Bertsch, J.; Öppinger, C.; Wohlers, H.; Kayastha, K.; Demmer, U.; Ermler, U.; Müller, V.: Molecular basis of the flavin‐based electron‐bifurcating caffeyl‐CoA reductase reaction. FEBS Letters 592 (3), pp. 332 - 342 (2018)

Demmer, J. K.; Chowdhury, N. P.; Selmer, T.; Ermler, U.; Buckel, W.: The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile. Nature Communications 8, 1577 (2017)

Warkentin, E.; Weidenweber, S.; Schühle, K.; Demmer, U.; Heider, J.; Ermler, U.: A rare polyglycine type II-like helix motif in naturally occurring proteins. Proteins: Structure, Function, and Bioinformatics 85 (11), pp. 2017 - 2023 (2017)

Weinert, T.; Olieric, N.; Cheng, R.; Brünle, S.; James, D.; Ozerov, D.; Gashi, D.; Vera, L.; Marsh, M.; Jaeger, K. et al.; Dworkowski, F.; Panepucci, E.; Basu, S.; Skopintsev, P.; Dorè, A. S.; Geng, T.; Cooke, R. M.; Liang, M.; Prota, A. E.; Paneels, V.; Nogly, P.; Ermler, U.; Schertler, G.; Hennig, M.; Steinmetz, M. O.; Wang, M.; Standfuss, J.: Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nature Communications 8, 542 (2017)

Bai, L.; Wagner, T.; Xu, T.; Hu, X.; Ermler, U.; Shima, S.: A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC. Angewandte Chemie, International Edition in English 56 (36), pp. 10806 - 10809 (2017)

Wagner, T.; Koch, J.; Ermler, U.; Shima, S.: Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction. Science 357 (6352), pp. 699 - 703 (2017)

Bai, L.; Fujishiro, T.; Huang, G.; Koch , J.; Takabayashi, A.; Yokono , M.; Tanaka , A.; Xu, T.; Hu , X.; Ermler, U. et al.; Shima , S.: Towards artificial methanogenesis: biosynthesis of the [Fe]-hydrogenase cofactor and characterization of the semi-synthetic hydrogenase. Faraday Discussions 198 (37), pp. 37 - 58 (2017)

Konjik, V.; Brünle, S.; Demmer, U.; Vanselow, A.; Sandhoff, R.; Ermler, U.; Mack, M.: The Crystal Structure of RosB: Insights into the Reaction Mechanism of the First Member of a Family of Flavodoxin-like Enzymes. Angewandte Chemie, International Edition in English 56 (4), pp. 1146 - 1151 (2017)

Weidenweber, S.; Schühle, K.; Demmer, U.; Warkentin, E.; Ermler, U.; Heider, J.: Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases. Scientific Reports 7, 39674 (2017)

Demmer, J. K.; Rupprecht, F. A.; Eisinger, M. L.; Ermler, U.; Langer, J. D.: Ligand binding and conformational dynamics in a flavin-based electron-bifurcating enzyme complex revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. FEBS Letters 590 (24), pp. 4472 - 4479 (2016)

Wagner , T.; Ermler, U.; Shima, S.: The methanogenic CO₂ reducing-and-fixing enzyme is bifunctional and contains 46 [4Fe-4S] clusters. Science Magazine 354 (6308), pp. 114 - 117 (2016)