Research Interests

Peng, W.; Zhou, T.; Hu, L.; Vankann, V.; Bohn, T.; Bopp, T.; Kuan, S. L.; Weil, T.: Autonomous Activation of a Gated Chemiluminescent Photosensitizer Enables Targeted Photodynamic Therapy in Tumor Cells. Journal of the American Chemical Society 147 (31), pp. 27822 - 27834 (2025)

Schauenburg, D.; Gao, B.; Rochet, L. N. C.; Schüler, D.; Coelho, J. A. S.; Ng, D. Y. W.; Chudasama, V.; Kuan, S. L.; Weil, T.: Macrocyclic Dual‐Locked "Turn‐On" Drug for Selective and Traceless Release in Cancer Cells. Angewandte Chemie International Edition 63 (18), e202314143 (2024)

Zegota, M. M.; Müller, M.; Lantzberg, B.; Kizilsavas, G.; Coelho, J. A. S.; Moscariello, P.; Martínez Negro, M.; Morsbach, S.; Gois, P. M. P.; Wagner, M. et al.; Ng, D. Y. W.; Kuan, S. L.; Weil, T.: Dual Stimuli-Responsive Dynamic Covalent Peptide Tags: Toward Sequence-Controlled Release in Tumor-like Microenvironments. Journal of the American Chemical Society 143 (41), pp. 17047 - 17058 (2021)

Xu, L.; Silva, M. J.S.A.; Coelho, J. A. S.; Borho, J.; Stadler, N.; Barth, H.; Kuan, S. L.; Weil, T.: Chemoselective dual functionalization of proteins via 1,6-addition of thiols to trifunctional N-alkylpyridinium. Nature Communications 16 (1), 5278 (2025)

Xu, L.; Silva, M. S. J. S. A.; Góis, P.; Kuan, S. L.; Weil, T.: Chemoselective cysteine or disulfide modification via single atom substitution in chloromethyl acryl reagents. Chemical Science 12 (40), pp. 13321 - 13330 (2021)

Xu, L.; Kuan, S. L.; Weil, T.: Contemporary Approaches for Site‐selective Dual Functionalization of Proteins. Angewandte Chemie International Edition 60 (25), pp. 13757 - 13777 (2021)

Lantzberg, B.; Zeyn, Y.; Forster, R.; Lin, J.; Schauenburg, D.; Hieber, C.; Nuhn, L.; Zhou, T.; Silva, M. J.S.A.; Koynov, K. et al.; Jiang, H.-L.; Kuan, S. L.; Bros, M.; Opatz, T.; Weil, T.: Glycogen-inspired trimannosylated serum albumin nanocarriers for targeted delivery of toll-like receptor 7/8 agonists to immune cells and liver. Journal of Controlled Release 382, 113705 (2025)

Raabe, M.; Heck, A.; Führer, S.; Schauenburg, D.; Pieszka, M.; Wang, T.; Zegota, M. M.; Nuhn, L.; Ng, D. Y. W.; Kuan, S. L. et al.; Weil, T.: Assembly of pH-Responsive Antibody-Drug-Inspired Conjugates. Macromolecular Bioscience 22 (2), 2100299 (2022)

Kuan, S. L.; Fischer, S.; Hafner, S.; Wang, T.; Syrovets, T.; Liu, W.; Tokura, Y.; Ng, D. Y. W.; Riegger, A.; Förtsch, C. et al.; Jäger, D.; Barth, T. F. E.; Simmet, T.; Barth, H.; Weil, T.: Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins. Advanced Science 5 (8), 1701036 (2018)