Infrastructure

The Mass Spectrometry Core Facility plays a crucial role in the institute's direction in various scientific frontiers of sustainability, defect engineering, biomedicine and synthetic biochemistry. The Facility houses various instruments for imaging mass spectrometry for the analysis of chemically and biologically modified surfaces. The MS Team is actively involved in method development to address a multitude of interdisciplinary questions, together with various groups within the institute.
Internal service measurements with ESI and MALDI (Synapt G2-Si and rapifleX) are provided as well by the mass spectrometry staff. Selected instruments (Advion CMS) can be used in self-service after the required introduction by our staff is obtained.

Service Measurements: Forms for ESI, MALDI and exact mass measurements can be found in the MPI-P intranet: forms for analytics and spectroscopy.

Self-service: The Advion ESI/APCI-MS instruments can be used in self-service after an introduction by our technical staff. Please contact Jutta Schnee or Stephan Türk to get the required introduction. For Advion LC-ESI-MS, please contact Maria Jose da Silva.

For analytical questions beyond routine measurements, please contact Seah-Ling Kuan or Maria Jose da Silva for further discussions.

Mass Spectrometers

Bruker Rapiflex MALDI-TOF/TOF MS

Specialized MALDI-TOF instrument with MS/MS fragmentation and MS imaging capability. more

Waters Synapt ESI/MALDI-Q-IM-ToF MS

ESI/MALDI-TOF instrument employing MS/MS capabilities and ion mobility separation. more

Iontof TOF.SIMS NCS

ToF-SIMS instrument providing surface spectrometry, imaging and depth-profiling of vacuum-compatible samples. more

Advion ESI-Q-MS

ESI-Q-MS instrument with sample introduction directly from TLC-plates, syringe pump or from associated UHPLC. more

Advion APCI-Q-MS

APCI/ASAP-Q-MS instrument with sample introduction via TLC plates, melting point capillary and direct injection. more

For internal users, additional details on MS techniques is provided on our intranet in the Experts-Wiki.

Auxiliary Devices

_Nano/(U)HPLC
 

_{for separation of protein samples before deposition onto MALDI targets}

_{Bruker Proteineer fc II Spotter}

_{for deposition of LC-fractions and MALDI matrices onto MALDI plates}

_{HTX TM Sprayer}
 

_{for matrix-coating of MALDI Imaging samples}
 

_{Resch MM400 ball mill}

_{for solvent free sample preparation and homogenization}