Publications of Hartmut Michel

Hunte, C.; Koepke, J.; Lange, C.; Roßmanith, T.; Michel, H.: Structure at 2.3 Å resolution of the cytochrome bc₁ complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment. Structure 8 (6), pp. 669 - 684 (2000)

Pfitzner, U.; Hoffmeier, K.; Harrenga, A.; Kannt, A.; Michel, H.; Bamberg, E.; Ludwig, B.: Tracing the D-Pathway in Reconstituted Site-Directed Mutants of Cytochrome c Oxidase from Paracoccus denitrificans. Biochemistry 39 (23), pp. 6756 - 6762 (2000)

Rengers, J.-U.; Touchard, G.; Decourt, C.; Deret, S.; Michel, H.; Cogné, M.: Heavy and light chain primary structures control IgG3 nephritogenicity in an experimental model for cryocrystalglobulinemia. Blood 95 (11), pp. 3467 - 3472 (2000)

Ruitenberg, M.; Kannt, A.; Bamberg, E.; Ludwig, Bernd; Michel, H.; Fendler, K.: Single-electron reduction of the oxidized state is coupled to proton uptake via the K pathway in Paracoccus denitrificans cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America 97 (9), pp. 4632 - 4636 (2000)

Chen, I.-P.; Mathis, P.; Koepke, J.; Michel, H.: Uphill Electron Transfer in the Tetraheme Cytochrome Subunit of the Rhodopseudomonas viridis Photosynthetic Reaction Center:  Evidence from Site-Directed Mutagenesis. Biochemistry 39 (13), pp. 3592 - 3602 (2000)

Charnock, J. M.; Dreusch, A.; Körner, H.; Neese, F.; Nelson, J.; Kannt, A.; Michel, H.; Garner, C. D.; Kroneck, P. M.H.; Zumft, W. G.: Structural investigations of the Cu_A centre of nitrous oxide reductase from Pseudomonas stutzeri by site-directed mutagenesis and X-ray absorption spectroscopy. European Journal of Biochemistry 267 (5), pp. 1368 - 1381 (2000)

Venturi, M.; Rimons, A.; Gerchman, Y.; Hunte, C.; Padan, E.; Michel, H.: The Monoclonal Antibody 1F6 Identifies a pH-dependent Conformational Change in the Hydrophilic NH₂ Terminus of NhaA Na⁺/H⁺ Antiporter of Escherichia coli. The Journal of Biological Chemistry 271 (7), pp. 4734 - 4742 (2000)

Hampe, W.; Voss, R.-H.; Haase, W.; Boege, F.; Michel, H.; Reiländer, H.: Engineering of a proteolytically stable human β₂-adrenergic receptor/maltose-binding protein fusion and production of the chimeric protein in Escherichia coli and baculovirus-infected insect cells. Journal of Biotechnology 77 (2-3), pp. 219 - 234 (2000)

Behr, J.; Michel, H.; Mäntele, W.; Hellwig, P.: Functional Properties of the Heme Propionates in Cytochrome c Oxidase from Paracoccus denitrificans. Evidence from FTIR Difference Spectroscopy and Site-Directed Mutagenesis. Biochemistry 39 (6), pp. 1356 - 1363 (2000)

Harrenga, A.; Reincke, B.; Rüterjans, H.; Ludwig, B.; Michel, H.: Structure of the soluble domain of cytochrome c₅₅₂ from Paracoccus denitrificans in the oxidized and reduced states. Journal of Molecular Biology (London) 295 (3), pp. 667 - 678 (2000)

Schiller, H.; Haase, W.; Molsberger, E.; Janssen, P.; Michel, H.; Reiländer, H.: The human ET(B) endothelin receptor heterologously produced in the methylotrophic yeast Pichia pastoris shows high-affinity binding and induction of stacked membranes. Receptors and Channels 7 (2), pp. 93 - 107 (2000)

Kannt, A.; Pfitzner, U.; Ruitenberg, M.; Hellwig, P.; Ludwig, B.; Mäntele, W.; Fendler, K.; Michel, H.: Mutation of Arg-54 Strongly Influences Heme Composition and Rate and Directionality of Electron Transfer in Paracoccus denitrificans Cytochrome c Oxidase. The Journal of Biological Chemistry 274 (53), pp. 37974 - 37981 (1999)

Kuglstatter, A.; Hellwig, P.; Fritzsch, G.; Wachtveitl, J.; Oesterhelt, D.; Mäntele, W.; Michel, H.: Identification of a hydrogen bond in the Phe M197→Tyr mutant reaction center of the photosynthetic purple bacterium Rhodobacter sphaeroides by X-ray crystallography and FTIR spectroscopy. FEBS Letters 463 (1-2), pp. 169 - 174 (1999)

Michel, H.: Proton pumping by cytochrome c oxidase. Nature 402 (6762), pp. 602 - 603 (1999)

Lancaster, C. R. D.; Kröger, A.; Auer, M.; Michel, H.: Structure of fumarate reductase from Wolinella succinogenes at 2.2 Å resolution. Nature 402 (6760), pp. 377 - 385 (1999)

Harrenga, A.; Michel, H.: The cytochrome c oxidase from Paracoccus denitrificans does not change the metal center ligation upon reduction. The Journal of Biological Chemistry 274 (47), pp. 33296-9 - 33299 (1999)

Michel, H.: Cytochrome c Oxidase:  Catalytic Cycle and Mechanisms of Proton Pumping-A Discussion. Biochemistry 38 (46), pp. 15129 - 15140 (1999)

Tandori, J.; Sebban, P.; Michel, H.; Baciou, L.: In Rhodobacter sphaeroides Reaction Centers, Mutation of Proline L209 to Aromatic Residues in the Vicinity of a Water Channel Alters the Dynamic Coupling between Electron and Proton Transfer Processes. Biochemistry 38 (40), pp. 13179 - 13187 (1999)

Pfitzner, U.; Kirichenko, A.; Konstantinov, A. A.; Mertens, M.; Wittershagen, A.; Kolbesen, B. O.; Steffens, G. C.M.; Harrenga, A.; Michel, H.; Ludwig, B.: Mutations in the Ca²⁺ binding site of the Paracoccus denitrificans cytochrome c oxidase. FEBS Letters 456 (3), pp. 365 - 369 (1999)

MacMillan, F.; Kannt, A.; Behr, J.; Prisner, T.; Michel, H.: Direct Evidence for a Tyrosine Radical in the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide. Biochemistry 38 (29), pp. 9179 - 9184 (1999)