Publications of Florian Wilfling

Wilfling, F.; Lee, C.-W.; Erdmann, P. S.; Baumeister, W.: Autophagy ENDing unproductive phase-separated endocytic protein deposits. Autophagy 17 (10), pp. 3264 - 3265 (2021)

Erdbrügger, P.; Wilfling, F.: p62 condensates are a hub for proteasome-mediated protein turnover in the nucleus. Proceedings of the National Academy of Sciences of the United States of America 118 (37), e2113647118 (2021)

Erdmann, P. S.; Hou, Z.; Klumpe, S.; Khavnekar, S.; Beck, F.; Wilfling, F.; Plitzko, J. M.; Baumeister, W.: In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Nature Communications 12 (1), 5364 (2021)

Wilfling, F.; Lee, C.-W.; Erdmann, P. S.; Zheng, Y.; Sherpa, D.; Jentsch, S.; Pfander, B.; Schulman, B. A.; Baumeister, W.: A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits. Molecular Cell 80 (5), pp. 764 - 778 (2020)

Bittmann, J.; Grigaitis, R.; Galanti, L.; Amarell, S.; Wilfling, F.; Matos, J.; Pfander, B.: An advanced cell cycle tag toolbox reveals principles underlying temporal control of structure-selective nucleases. eLife 9, e52459 (2020)

Lee, C.-W.; Wilfling, F.; Ronchi, P.; Allegretti, M.; Mosalaganti, S.; Jentsch, S.; Beck, M.; Pfander, B.: Selective autophagy degrades nuclear pore complexes. Nature Cell Biology 22 (2), pp. 159 - 166 (2020)

Frank, D. O.; Dengjel, J.; Wilfling, F.; Kozjak-Pavlovic, V.; Häcker, G.; Weber, A.: The Pro-Apoptotic BH3-Only Protein Bim Interacts with Components of the Translocase of the Outer Mitochondrial Membrane (TOM). PLoS One 10 (4), e0123341 (2015)

Wilfling, F.; Haas, J. T.; Walther, T. C.; Farese, R. V.: Lipid droplet biogenesis. Current Opinion in Cell Biology 29, pp. 39 - 45 (2014)

Wilfling, F.; Thiam, A. R.; Olarte, M.-J.; Wang, J.; Beck, R.; Gould, T. J.; Allgeyer, E. S.; Pincet, F.; Bewersdorf, J.; Farese, R. V. et al.; Walther, T. C.: Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting. eLife 3, e01607 (2014)

Thiam, A. R.; Antonny, B.; Wang, J.; Delacotte, J.; Wilfling, F.; Walther, T. C.; Beck, R.; Rothman, J. E.; Pincet, F.: COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function. Proceedings of the National Academy of Sciences of the United States of America 110 (33), pp. 13244 - 13249 (2013)

Mejhert, N.; Wilfling, F.; Esteve, D.; Galitzky, J.; Pellegrinelli, V.; Kolditz, C.-I.; Viguerie, N.; Tordjman, J.; Näslund, E.; Trayhurn, P. et al.; Lacasa, D.; Dahlman, I.; Stich, V.; Lång, P.; Langin, D.; Bouloumié, A.; Clément, K.; Rydén, M.: Semaphorin 3C is a novel adipokine linked to extracellular matrix composition. Diabetologia 56 (8), pp. 1792 - 1801 (2013)

Krahmer, N.; Hilger, M.; Kory, N.; Wilfling, F.; Stoehr, G.; Mann, M.; Farese Jr., R. V.; Walther, T. C.: Protein Correlation Profiles Identify Lipid Droplet Proteins with High Confidence. Molecular and Cellular Proteomics 12 (5), pp. 1115 - 1126 (2013)

Wilfling, F.; Wang, H.; Haas, J. T.; Krahmer, N.; Gould, T. J.; Uchida, A.; Cheng, J.-X.; Graham, M.; Christiano, R.; Fröhlich, F. et al.; Liu, X.; Buhman, K. K.; Coleman, R. A.; Bewersdorf, J.; Farese, R. V.; Walther, T. C.: Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. Developmental Cell 24 (4), pp. 384 - 399 (2013)

Wilfling, F.; Weber, A.; Potthoff, S.; Vögtle, F.-N.; Meisinger, C.; Paschen, S. A.; Häcker, G.: BH3-only proteins are tail-anchored in the outer mitochondrial membrane and can initiate the activation of Bax. Cell Death and Differentiation 19 (8), pp. 1328 - 1336 (2012)

Krahmer, N.; Guo, Y.; Wilfling, F.; Hilger, M.; Lingrell, S.; Heger, K.; Newman, H. W.; Schmidt-Supprian, M.; Vance, D. E.; Mann, M. et al.; Farese, R. V.; Walther, T. C.: Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Cell Metabolism 14 (4), pp. 504 - 515 (2011)

Weber, A.; Paschen, S. A.; Heger, K.; Wilfling, F.; Frankenberg, T.; Bauerschmitt, H.; Seiffert, B. M.; Kirschnek, S.; Wagner, H.; Häcker, G.: Bim_s-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins. The Journal of Cell Biology: JCB 177 (4), pp. 625 - 636 (2007)