Publications of Ana J. Garcia Saez

Murad, F.; Garcia Saez, A. J.: Bcl-xL inhibits tBid and Bax via distinct mechanisms. Faraday Discussions 232, pp. 86 - 102 (2021)

Danial, J. S. H.; Shalaby, R.; Cosentino, K.; Mahmoud, M. M.; Medhat, F.; Klenerman, D.; Garcia Saez, A. J.: DeepSinse: deep learning-based detection of single molecules. Bioinformatics 37 (21), pp. 3998 - 4000 (2021)

Cosentino, K.; Hermann, E.; von Kügelgen, N.; Unsay, J. D.; Ros, U.; García-Sáez, A. J.: Force Mapping Study of Actinoporin Effect in Membranes Presenting Phase Domains. Toxins 13 (9), 669 (2021)

Ros, U.; Pedrera, L.; Garcia-Saez, A. J.: Techniques for studying membrane pores. Current Opinion in Structural Biology 69, pp. 108 - 116 (2021)

Pedrera, L.; Espiritu, R. A.; Ros, U.; Weber, J.; Schmitt, A.; Stroh, J.; Hailfinger, S.; von Karstedt, S.; García-Sáez, A. J.: Ferroptotic pores induce Ca²⁺ fluxes and ESCRT-III activation to modulate cell death kinetics. Cell Death and Differentiation 28 (5), pp. 1644 - 1657 (2021)

Dadsena, S.; Zollo, C.; García-Sáez, A. J.: Mechanisms of mitochondrial cell death. Biochemical Society Transactions 49 (2), pp. 663 - 674 (2021)

Dadsena, S.; Jenner, A.; García-Sáez, A. J.: Mitochondrial outer membrane permeabilization at the single molecule level. Cellular and Molecular Life Sciences 78 (8), pp. 3777 - 3790 (2021)

Serulla, M.; Ichim, G.; Stojceski, F.; Grasso, G.; Afonin, S.; Heulot, M.; Schober, T.; Roth, R.; Godefroy, C.; Milhiet, P.-E. et al.; Das, K.; García-Sáez, A. J.; Danani, A.; Widmann, C.: TAT-RasGAP_317-326 kills cells by targeting inner-leaflet–enriched phospholipids. Proceedings of the National Academy of Sciences of the United States of America 117 (50), pp. 31871 - 31881 (2020)

Shalaby, R.; Flores-Romero, H.; García-Sáez, A. J.: The Mysteries around the BCL-2 Family Member BOK. Biomolecules 10, 1638 (2020)

Flores-Romero, H.; García-Sáez, A. J.: Lipids glue BAK dimers together. Nature Structural & Molecular Biology 27 (11), pp. 1003 - 1004 (2020)

Flores‐Romero, H.; Ros, U.; Garcia-Saez, A. J.: Pore formation in regulated cell death. The EMBO Journal 39 (23), e105753 (2020)

García-Sáez, A. J.: The BCL-2 family saga. Nature Reviews Molecular Cell Biology 21 (10), pp. 564 - 565 (2020)

Lindenboim, L.; Grozki, D.; Amsalem-Zafran, A. R.; Peña-Blanco, A.; Gundersen, G. G.; Borner, C.; Hodzic, D.; García-Sáez, A. J.; Worman, H. J.; Stein, R.: Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins. Cell Death Discovery 6, 90 (2020)

Peña-Blanco, A.; Haschka, M. D.; Jenner, A.; Zuleger, T.; Proikas-Cezanne, T.; Villunger, A.; García-Sáez, A. J.: Drp1 modulates mitochondrial stress responses to mitotic arrest. Cell Death and Differentiation 27 (9), pp. 2620 - 2634 (2020)

Diestelkoetter-Bachert, P.; Beck, R.; Reckmann, I.; Hellwig, A.; Garcia Saez, A. J.; Zelman-Hopf, M.; Hanke, A.; Nunes Alves, A.; Wade, R. C.; Mayer, M. P. et al.; Wieland, F.: Structural characterization of an Arf dimer interface: molecular mechanism of Arf-dependent membrane scission. FEBS Letters 594 (14), pp. 2240 - 2253 (2020)

Ros Quincoces, U. L.; Pedrera, L.; Garcia Saez, A. J.: Partners in Crime: The Interplay of Proteins and Membranes in Regulated Necrosis. International Journal of Molecular Sciences 21 (7), 2412 (2020)

Kuwana, T.; King, L. E.; Cosentino, K.; Suess, J.; Garcia-Saez, A. J.; Garcia-Saez, A. J.; Gilmore, A. P.; Newmeyer, D. D.: Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization. Journal of Biological Chemistry 295 (6), pp. 1623 - 1636 (2020)

Singh, P. K.; Roukounakis, A.; Weber, A.; Das, K. K.; Sohm, B.; Villunger, A.; Garcia Saez, A. J.; Häcker, G.: Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim. Cell Death and Differentiation 27 (2), pp. 434 - 450 (2020)

Hertlein, V.; Flores-Romero, H.; Das, K. K.; Fischer, S.; Heunemann, M.; Calleja-Felipe, M.; Knafo, S.; Hipp, K.; Harter, K.; Fitzgerald, J. C. et al.; García-Sáez, A. J.: MERLIN: a novel BRET-based proximity biosensor for studying mitochondria-ER contact sites. Life science alliance 3 (1), e201900600 (2019)

Flores-Romero, H.; Landeta, O.; Ugarte-Uribe, B.; Cosentino, K.; García-Porras, M.; García-Sáez, A. J.; Basañez, G.: BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL. Cell Death and Differentiation 26 (10), pp. 1880 - 1894 (2019)