Using state of the art equipment, we are advancing current characterization methodology of polymers in biological media as well as performing rigorous characterization of synthetic and biological polymers.
Besides our own research, the polymer analytics group is a core facility for the entire Max Planck Institute for Polymer Research. We use the following physicochemical characterization techniques on a daily basis:
We regularly tailor the characterization approach for each new sample to include optimization of measurement conditions (solvent, temperature, columns, filtration, and separation techniques). With our focus on a combination of various physicochemical techniques we have the possibility to provide characterization on the forefront of polymer analytics.
Dr. Svenja Morsbach visited the University of Hasselt for giving a lecture at the Nanotechnology Crossing Borders symposium on September 26th, 2019 about the "Characterization of Nanocarriers in Biological Media". It was a great event - many thanks for the invitation!
Successful PhD Defense
Dr. Domenik Prozeller defended his thesis about "The immune system dependency of the protein corona" on September 24th, 2019. Congrats and all the best!
We are very proud we could host the 1st annual review meeting of our EU project VES4US at our institute here in Mainz! With our partners from all over europe, we had a very productive and enjoyable time from July 22-24, 2019. Thanks for coming!
Group trip to ZDF!
Our group visited the TV broadcasting station of ZDF (second german television) in Mainz Lerchenberg. It was a great day meeting the "Mainzelmännchen", learning what all the buttons do in the studios/directing rooms and having fun with the greenscreen!
Check out our newest research article in Advanced Science: "Prevention of Dominant IgG Adsorption on Nanocarriers in IgG-enriched Blood Plasma by Clusterin Precoating" by Domenik Prozeller et al. We are happy this study is now featured on the back cover!
Check out our newest minireview, which was just published as an accepted article in Angewandte Chemie International Edition: "Possibilities and Limitations of Different Separation Techniques for the Analysis of the Protein Corona" by Claudia Weber, Svenja Morsbach and Katharina Landfester.
Congratulations to the PhD defense!
We congratulate Dr. Claudia Weber to her successful PhD defense on December 19th. She submitted her thesis about the "Flow-based techniques for the analysis of nanocarriers in biological environments".
In the project Ves4Us that runs for a total of three years, scientists from Italy, Ireland, Switzerland and Slovenia are now working together with the Max Planck Institute for Polymer Research (MPI-P) in Mainz. The focus is put on extracellular vesicles from a natural source for tailor-made nanomaterials, where the team at MPI-P works mainly on the surface modification of the carriers.
In the project "Loss of neurotrophic factors in neurodegenerative dementias: Back to the crossroads of proteins" (LODE) researchers are focusing on understanding more about the disease developments and -especially at MPIP - developing nanocarrier devices for the transport of drugs into brain cells. Funding is provided via the EU joint programme - Neurodegenerative Disease Research for three years.
Together with a team of three other young researchers, Claudia Weber and Solveig Bartelt from the MPIP won the prize for the best group presentation regarding current research challenges. The Leibniz Young Polymer Scientist Forum was held on June 28-29, 2018 at the DWI - Leibniz Institute for Interactive Materials in Aachen.
PhD defense successful!
We congratulate Dr. Johanna Simon to her successful PhD defense on June 19th. She submitted her thesis about the "Proteomic characterization of the biomolecular corona and its impact on cellular uptake".
Check out the latest review article just published online in Angewandte Chemie International Edition about "Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions" with contributions from different departments of the MPIP related to the focus topic of the institute!
Dr. Svenja Morsbach was invited as a lecturer to the Horizon 2020 Materials Networking School in Sofia, Bulgaria, held from March 21-23, 2018. The school was focused on "Biomaterials: synthesis and characterization".
Check out our newest publication "Beyond the protein corona: Lipids matter for biological response of nanocarriers" in Acta Biomaterialia!
The polymer analysis group went to try out a new indoor activity: Black light minigolf! After a lot of fun in the dark, the evening was spent with some delicious dinner. We are already looking forward to the next event!
Riccardo Wehr successfully finished his master thesis with the title „Korrelation der Primärstruktur von Xanthanen mit deren Verhalten in Lösung” which was conducted in cooperation with Jungbunzlauer Ladenburg.
At the Gordon Research Seminar, Julius Müller gave a presentation with the title "Coating Nanoparticles with Tunable Surfactants Enables Control Over Protein Adsorption". The seminar and the associated conference were held in Mount Snow, VT, USA from June 17 - 23, 2017.
Dr. Svenja Winzen was speaking at the NanoTech France 2017 Conference about "Providing an alternative to covalent stealth modification of nanomaterials by using tunable surfactants". Additionally, Claudia Weber gave a talk on "Asymmetrical flow field-flow fractionation: A new approach for analysis of the protein corona". The conference was held from June 28-30 in the Pôle Universitaire Léonard de Vinci in Paris.
The 22nd Kalorimetrietage took place in Braunschweig, Germany from June 7-9, 2017. Domenik Prozeller presented a poster with the title "Beyond the Protein Corona - Lipids Matter for Biological Response of Nanocarriers".
Julius Müller and Kristin Bauer published a paper in Biomaterials on "Coating nanoparticles with tunable surfactants facilitates control over the protein corona". The publication was featured in the latest issue of the newsletter Nanotechnology Weekly by NewsRX.
We congratulate Laura Müller for successfully passing her PhD defense on September 27, 2016! The title of her thesis was "Using the interactions of designed siRNA and DNA drug carrier systems with human blood plasma and its components for controlled drug delivery".
Julius Müller was given the opportunity to present his research project entitled "Probing Protein Adsorption on Surfactant-Coated Nanoparticles with Isothermal Titration Calorimetry" at the XIX ISBC (International Society for Biological Calorimetry) Conference in Basel held from June 22 - 24.
Poster Award at the 2016 International Symposium on Field- and Flow-Based Separations
Claudia Weber won the poster prize at the 18th International Symposium on Field- and Flow-Based Separations held in Dresden from May 22-26 2016. The title of the poster was "Analysis of the protein corona using asymmetrical flow field-flow fractionation".